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• In 2014, over 913,000 people were reported to be addicted to cocaine.
• Barbiturate Overdose is known to result in Pneumonia, severe muscle damage, coma and death.
• The United Nations Office on Drugs and Crime estimated the worldwide production of amphetamine-type stimulants, which includes methamphetamine, at nearly 500 metric tons a year, with 24.7 million abusers.
• 30% of emergency room admissions from prescription abuse involve opiate-based substances.
• Crack cocaine is derived from powdered cocaine offering a euphoric high that is even more stimulating than powdered cocaine.
• 100 people die every day from drug overdoses. This rate has tripled in the past 20 years.
• Only 9% of people actually get help for substance use and addiction.
• Methamphetamine blocks dopamine re-uptake, methamphetamine also increases the release of dopamine, leading to much higher concentrations in the synapse, which can be toxic to nerve terminals.
• Barbiturates are a class B drug, meaning that any use outside of a prescription is met with prison time and a fine.
• Statistics say that prohibition made Alcohol abuse worse, with more people drinking more than ever.
• Ketamine is popular at dance clubs and "raves", unfortunately, some people (usually female) are not aware they have been dosed.
• Approximately 122,000 people have admitted to using PCP in the past year.
• Abuse of the painkiller Fentanyl killed more than 1,000 people.
• Stimulants such as caffeine can be found in coffee, tea and most soft drinks.
• Use of amphetamines is increasing among college students. One study across a hundred colleges showed nearly 7% of college students use amphetamines illegally. Over 25% of students reported use in the past year.
• In medical use, there is controversy about whether the health benefits of prescription amphetamines outweigh its risks.
• Fentanyl is a powerful synthetic opioid analgesic that is similar to morphine but is 50 to 100 times more potent.
• Alcoholism has been found to be genetically inherited in some families.
• These physical signs are more difficult to identify if the tweaker has been using a depressant such as alcohol; however, if the tweaker has been using a depressant, his or her negative feelings - including paranoia and frustration - can increase substantially.
• Out of 2.6 million people who tried marijuana for the first time, over half were under the age of 18.