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• 30% of emergency room admissions from prescription abuse involve opiate-based substances.
• 4.4 million teenagers (aged 12 to 17) in the US admitted to taking prescription painkillers, and 2.3 million took a prescription stimulant such as Ritalin.
• Stimulants can increase energy and enhance self esteem.
• In medical use, there is controversy about whether the health benefits of prescription amphetamines outweigh its risks.
• Afghanistan is the leading producer and cultivator of opium worldwide and manufactures 74% of illicit opiates. However, Mexico is the leading supplier to the U.S
• Methamphetamine blocks dopamine re-uptake, methamphetamine also increases the release of dopamine, leading to much higher concentrations in the synapse, which can be toxic to nerve terminals.
• Meth users often have bad teeth from poor oral hygiene, dry mouth as meth can crack and deteriorate teeth.
• Non-pharmaceutical fentanyl is sold in the following forms: as a powder; spiked on blotter paper; mixed with or substituted for heroin; or as tablets that mimic other, less potent opioids.
• Women born after World War 2 were more inclined to become alcoholics than those born before 1943.
• Studies show that 11 percent of male high schoolers have reported using Steroids at least once.
• Inhalants go through the lungs and into the bloodstream, and are quickly distributed to the brain and other organs in the body.
• Illicit drug use in the United States has been increasing.
• 3 Million people in the United States have been prescribed Suboxone to treat opioid addiction.
• Cocaine was originally used for its medical effects and was first introduced as a surgical anesthetic.
• Relapse is the return to drug use after an attempt to stop. Relapse indicates the need for more or different treatment.
• Only 9% of people actually get help for substance use and addiction.
• Methadone came about during WW2 due to a shortage of morphine.
• Heroin is usually injected into a vein, but it's also smoked ('chasing the dragon'), and added to cigarettes and cannabis. The effects are usually felt straightaway. Sometimes heroin is snorted the effects take around 10 to 15 minutes to feel if it's used in this way.
• Heroin addiction was blamed for a number of the 260 murders that occurred in 1922 in New York (which compared with seventeen in London). These concerns led the US Congress to ban all domestic manufacture of heroin in 1924.
• Over 2.3 million people admitted to have abused Ketamine.