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• 7.5 million have used cocaine at least once in their life, 3.5 million in the last year and 1.5 million in the past month.
• Cocaine increases levels of the natural chemical messenger dopamine in brain circuits controlling pleasure and movement.
• Afghanistan is the leading producer and cultivator of opium worldwide and manufactures 74% of illicit opiates. However, Mexico is the leading supplier to the U.S
• Prescription drug spending increased 9.0% to $324.6 billion in 2015, slower than the 12.4% growth in 2014.
• Cocaine use is highest among Americans aged 18 to 25.
• LSD disrupts the normal functioning of the brain, making you see images, hear sounds and feel sensations that seem real but aren't.
• Krododil users rarely live more than one year after taking it.
• Crack cocaine is the crystal form of cocaine, which normally comes in a powder form.
• Meperidine (brand name Demerol) and hydromorphone (Dilaudid) come in tablets and propoxyphene (Darvon) in capsules, but all three have been known to be crushed and injected, snorted or smoked.
• In 2005, 4.4 million teenagers (aged 12 to 17) in the US admitted to taking prescription painkillers, and 2.3 million took a prescription stimulant such as Ritalin. 2.2 million abused over-the-counter drugs such as cough syrup. The average age for first-time users is now 13 to 14.
• Of the 500 metric tons of methamphetamine produced, only 4 tons is legally produced for legal medical use.
• Fentanyl works by binding to the body's opioid receptors, which are found in areas of the brain that control pain and emotions.
• Oxycontin has risen by over 80% within three years.
• Methamphetamine and amphetamine were both originally used in nasal decongestants and in bronchial inhalers.
• Women born after World War 2 were more inclined to become alcoholics than those born before 1943.
• 60% of teens who have abused prescription painkillers did so before age 15.
• Nearly half (49%) of all college students either binge drink, use illicit drugs or misuse prescription drugs.
• Stimulants such as caffeine can be found in coffee, tea and most soft drinks.
• In 2007, methamphetamine lab seizures increased slightly in California, but remained considerably low compared to years past.
• Only 9% of people actually get help for substance use and addiction.